Gene description for ITGA2
Gene name	integrin subunit alpha 2
Gene symbol	ITGA2
Other names/aliases	BR CD49B GPIa HPA-5 VLA-2 VLAA2
Species	Homo sapiens
Experiment description of studies that identified ITGA2 in Squamous carcinoma cells
1 Experiment ID 411 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 20124223    Organism Homo sapiens Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK. Journal name Mol Cell Proteomics Publication year 2010 Sample Squamous carcinoma cells Sample name Squamous carcinoma cell (A431) Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV100050: EV-METRIC:22%
2 Experiment ID 1129 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 23954818    Organism Homo sapiens Experiment description Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. Authors Garnier D, Magnus N, Meehan B, Kislinger T, Rak J. Journal name Exp Cell Res Publication year 2013 Sample Squamous carcinoma cells Sample name Mesenchymal A431 (SHE78-7/TGF. treated) Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130185: EV-METRIC:11%
3 Experiment ID 1131 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 23954818    Organism Homo sapiens Experiment description Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state. Authors Garnier D, Magnus N, Meehan B, Kislinger T, Rak J. Journal name Exp Cell Res Publication year 2013 Sample Squamous carcinoma cells Sample name Mesenchymal A431 (SHE78-7/TGF. treated) Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK EV130185: EV-METRIC:11%